I wonder, Veks, do you mean to leave all the D&D stuff folded together? I know D&D has a million worlds, but maybe list some of the more popular settings in there? For instance, I like Eberron and I don't mind Forgotten Realms, but maybe Dark Sun is right out? I know you said it's general, but I think it's sort of an important distinction for D&D... kind of like in the WoD. I have no idea about nWoD... I love WoD Mage... would not touch Werewolf without some serious convincing though.
Maybe that's too detailed.