Okay, so I thought up a potential setting for all this busty bimbo nonsense.
A grand city, of sweeping vistas and scenic riverways. A city founded on the combination of magic and technology, working in harmony to provide for the people. A place of higher education, political intrigue, and very deep, dark shadows. Within those shadows, everything from monsters to assassins to rowdy drunks to-
You don't care about any of that. You're a Bimbo, here to save the day. Come what may, your shoes shall be forever impractical and your makeup forever perfect. What you DO care about is the city has plenty of amazing fashions and it seems like something's always going on sale! Whether it's the classic busty barbarian look from Carrie's Hunts, the futuristic neon latex of Net-Skirts, or just the cavalcade of pop culture references from Hot Topic, there's a little something for everyone. And don't forget your favorite coffee, where would Bimbos be without hot, sugary drinks?
Basically, the setting is set up to accommodate whatever I dang well feel like, to the point that, since we have multiple interested participants, I could very easily run two groups, both having adventures and occasionally interacting, or at least hearing rumors of each other's exploits!