I got Pathfinder, SR4, MM 2 & 3 and CoC on it
My groups haven't taken to Pathfinder, at least not yet. I have the Beginner Box and one of my players has the core book and is at least somewhat interested in trying it out in the future.
Shadowrun will likely be my next purchase for Hero Lab. It is especially useful for point based systems I find. It would be nice if they had a GURPS version, though most of my books are 3rd rather than 4th edition for that system.
I opted to not update to M&M 3, keeping with 2nd Edition. I really love my 2nd Edition books and the ruleset. Do you play one or both and if so do you prefer the 2nd or 3rd edition?
As for CoC I don't think my group will switch to electronic chargen, we have a thing about making those characters gathered around a small table with only a lamp to light us as we make our characters and play. Good times.