And now I Can't help but think about how the movies fit into the Continuity of the game. Let's just take out the zombie apocalypse, and Alice too (Since there will be a fifth movie, she probably dies in that anyway, and the Zombie outbreak may even be cured..who knows. O_o)
But...taking out those elements...the movies (Especially this one) could very easily fit before the 5th game.
Chris Redfield is in the movie, of course, and he seems like he's never faced Las Plagas before, but he also seems like he knows about them.
Which brings to that other fact..Las Plagas are definetly in. The Zombies this time around sprout tentacles from their mouth, clearly because of the Parasite, though this is never stated in the movie that it is a parasite, anyone who's played RE4 will know.
The most compelling reason for it to fit into Continuity is because...*gasp* The movie actually explains just why the hell Jill was with Wesker in RE5. (Unless that DLC for RE5 cleared it up). In the movie, Jill is captured along with the other survivors that we saw in the Third movie, and has the mind control device planted on her as soon as she is captured. At the end of the movie, we see her again (or for the first time...I'm not really sure. O_o) with the device on her chest, commanding Umbrella Soldiers.
*gasp* Wesker is also in the movie (Of course) and surprise surprise, he's about as invulnerable as GOD. He gets blown up at the end by some kind of neutron/Anti-Matter Bomb that first expands then shinks whatever it blasted away into nothingness But geez...
I mean, first of all, he survives a plane crash. Then he survives some kind of Coin-Shotgun blast THROUGH THE MOUTH, plus being riddled with bullets...come on..we all know he's still alive. >_>
He's also clearly infected himself with Las Plagas, because he sprouts the mouth tentacles as well, thus placing at least the fourth movie (And the movies as a whole) after RE4.
Also, Dr. Salvador/Las Gigante is also in the movie...well, sort of...a Type of Dr. Salvador-Esque enemy...he has a bag over his head, and uses a gigantic megaton hammer/axe as a weapon...which obviously someone had to make for him before releasing him, cause those things aren't just laying around. O-o
So yeah..outside of Alice, and the Zombie Apocalypse, the movies actually could fit into Canon rather well. O_o