I just read Midnight Mass by F Paul Wilson and was so inspired that I thought this deserved its own topic.
The world is being overrun by vampires. Crazed bloodsucking hordes. They don't want to romance you, they don't want to get into your knickers, they just want your blood. The cool calculating ones, the really powerful and old ones, are in charge. They have vampiric bodyguards and feral, barbaric wolflike vampires at their service.
The human race is in hiding. The rest of the world is gone. Asia, Europe, all under subjugation. The USA is left, and there's not much visible resistance because the leaders have all been turned into vampires. All that's left are pockets of people who are struggling to survive, or just planning to go down fighting. By day, human cowbows roam the streets, searching for unlucky captures to bring to their vampiric masters. These humans are the dregs of society - not yet turned, but promised an eternity of undeath if they turn against their human compatriots.
Children are especially prized. Women, especially pregnant women. Young women are brought to farms where not only do they serve as a renewable supply of blood, but also used as an occasional reward for cowboys who've done especially well. "Stud time", they call it, a day or two of being let loose among the women prisoners.
Skilled technicians are coerced, through the rape and physical violence to their families, to run whatever technology is left.
The prey are running. And hiding. Women trade sexual favours for food. Men are dragged, kicking and screaming, to their deaths. Occasionally, a cowboy is found killed, ambushed by outraged citizens. Even more rarely, a vampire is found dead, killed in self-defense.
Does this strike your fancy? There'll be horrific scenes of blood and gore in the game. Rape and murder aren't the most horrible things you'll find. Even more horrific are the depths the human race will sink to, to save their own skins. But in times of trouble, heroism shines through even more strongly. Who will you be?
Players, I need players. If someone wants to GM this game, all the better. But if not, I can :)