I am very interested in this, and I would also be interested in helping to organize the plot and the game itself, though I don't feel I could appropriately GM it since I have not yet done such a thing.
I'm a quick learner, and really great at organizational sorts of things. I like the idea of something of a local community, a small city in the Roman empire or somesuch... where players can meet and interact all together at a few different locations. They could easily exist as separate threads (I think, ex THE ROME GAME: The Fourm. or THE ROME GAME: The baths) That way individual RPs would not be hard, you can interact publicly and take it to PMS -- OR perhaps houses could have their own forums? I have no idea how much liberty with different forums folks here have, being a newb.
There are some thoughts for ya! I am interested in characters scholarly, perhaps a educated daughter of somebody important, a priestess, a philosopher. I need to research more on how patriarchal ROME was and whether or not it would be within the realm of believability to be a woman with a career.
Feel free to PM me if you'd like to partner up and start some planning!