Several portals opening up? Sounds like the Endless Frontier!
Ever played that OP? Maybe we could use that if you had. I could even help you with making the world.
Also 700 seems kind of high.
Also my 3 favorite manga/anime?
1) GaoGaiGar 2)G Gundam 3) Nanoha StrikerS
I have not played nor know anything about Endless Frontier. But as one said already about sci-fi and fantasy world connected by portals I intent somethin akin to that. As I already said; game starts in normal modern setting. Let's say in year 2012 (which is present dooms day year). The world does not come end but radically changes.
It's basically blend of several themes and universes. There can be classic gothic power vampires who use alien technology or human witch from faerie dimension hacking computer by using faerie magic. Blend of sci-fi and fantasy but origin wise they were unrelated but end up to same dimension.
So start point to each char is idea what they are and what they are capable; they could be alien species who is coming to earth (or exotic magical creature from magical dimension) or regular human 'mutated' to another creature. Same way you can think was your human original normal everyday student who got then affected one or two factors which came with blending of the dimensions.
Example you choose basic background you were musical arts student from London, but as vampires became more public you went 'Buffy' and started devote your life between studies and killing vampires. But then aliens came from deep space through malfunctioning warp engine and crash landed to London countryside they then started become your allies against vampires so you got alien tech to help kill vampires which so far you had used some occultic arts to do so.
I do not say you need to mix some sci-fi into your char or mix magic to your char. You could be USA best test pilots who tries out USA developed mecha which was intended for third world war but instead end up figth against aliens from space with it. Aliens who uses high tech.
Anycase thanks Niki315 help with folks in making the chars :). As I myself I am quite new to the system also so help is appreciated :).
Anycase I agree that 400 points is suitable limit, with max 50 extra points from defects so max amount of starting points is between 400-450 range. I intent that you do not yet face deity level threats. Mostly big gangs of sci-fi thugs with some powerful minions of bigger powers (as group, not solo). It's a year or two since the blending of the worlds and stuff to modern earth.