I want to run a oWoD game for vampires that are Caitiff this means have no clan (no social Caitiff must not be imprinted with any clan traits) and may be Thin-Blooded 14th or 15th Generation or Dhamphir the children of the last generation of true vampires.
The plot wou d be after Gehenna the Technocracy using Code: Regnorak unleashed hell on the Ancients as they awoke in miost cased nuking cities to get them as needed. This under a terrorist campaign by Al Queda. After they got done all the clans fell the Ventrue under direct assault by the Technocracy Men-in-Black. The remained Kindred are those with no blood ties and weak blood now granted support by the Technocracy. After the WEEK OF TERROR the global authority of the UN took over and under one government a new utopia has begun. Well all is not perfect a strict caste system is in place and vampires are pretty much well treated if they are discrete, each city has a BOARD OF DIRECTORS made up of stronger Caitiff (or those that fell in early with the Technocracy) that handle Kindred affairs. Each is self-sufficient and maintain the Traditions.
Humans fall into five castes the Deltas (do service jobs and the like, are usually attractive), Gammas (workers in factories, skilled trades), Betas (information specialists), Alphas (leader caste) and Epsilons (special types Technocracy mages, vampires, garou that are in the club, Banes and the like). You can guess who runs things. The same scale goes for the top caste Epsilons-Epsilons are only technomages vampires generally are lower but can become fairly influential.
Yes just like A BRAVE NEW WORLD the novel with vampires and behind the scenes lots of intrigue. The Warrens the barabric areas exist and have vampires not in the good side of the new government, humans that don't want in the system and remenants of the Sabbat some who have surviving Elders. Yes they do attack into the cities at times and cause problems.
Yes in the system humans know vampires exist are deemed by the government as the next evolution of humanity kind of like they are engineering humans for space or living in the sea. Outside the great cities its far different.