Just remember to do gruesome blood drinking scenes, even when the players top off. You can also throw top tier antagonists at the party (high wyrd changelings, werewolf packs, jagglings, slayer geists trying to restore the natural order) almost casually, since they can dust them without substantial risk to themselves. (especially if you use a house rule that vampires don't go into torpor from lethal damage until the end of the scene)
In my experience, nothing short of over 100 vampires can challenge a well fortified group of elders. (though that group of elders had accumulated an army of 300,000 soldiers in china, while the Camarilla came after them with an army of 3,000 ghouls, 250 vampires, and 15,000 blood slaves.)
Elders and covenants is something that comes up in Requiem which doesn't have much of a paralell in Masquerade. Basically, instead of the Camarilla and Sabatt (plus technically anarchs) there are six different factions a vampire can belong to (plus technically VII and Belial's Brood) which influence a vampire's political life a great deal.
The factions from an elder's perspective:
Invictus: Control more money than Jesus, stand at the top of a silly power structure, drink blood from a wine glass every day? Why the hell would anyone not want to be invictus? The handing 1 million dollars to neonates and seeing how much trouble they get into thing is fun too.
Carthians: Why the hell would an elder want to be a Carthian? You have to respect people, you don't get to be a leader just because you're old, and they keep doing these creepy sing alongs. On the other hand, they do have pretty good night classes on how to operate these mysterious "ATM" devices I hear so much about.
Lancea Sanctum: Only Elders can draw upon the true power of the Lord most high. Blot out the sun, launch spears from your eyes, transubstantiate lead into gold (or milk into blood) It's good to be the antichrist.
Circle of the Crone: If the Sanctum elders get to be the heirophants, Circle elders get to be pagan gods. Intensely customized high end magical power, horrific monsters at your beck and call... Maybe even a scary copse of trees to torment teenagers in. Just don't get shoved into your own oven.
Ordo Dracul: Endless youth, eternity to plot one's clever machinations... It's really incredible that Elders don't choose the Ordo Dracul. If only the hazing rituals weren't so painful and humiliating, trying to make completely and utterly sure those cowardly elders aren't going to use their power to steal the techniques of the ordo dracul to evade torpor, then run off back to their own covenant. Dracula is coming back, by the way.
Unaligned: The only sensible way to live is without rules. Unaligned elders have the best of all possible worlds when it comes to deciding their own destiny, and can create plans that the other covenants would reel at and call a blood hunt on. Then, of course, there are those elders who have simply given in to the red surrender, and bring chaos everywhere they go, their movements predicted by other vampires like hurricanes.
Belial's Brood: The elders of Belial's Brood are the scariest fucking monsters you will ever meet. Ever. Coincidentally, elders of the Brood are virtually unheard of, and most of them got that way through mass diablerie. These beasts tend to have short cycles of intense activity, followed by decades or centuries of torpor, quite often staked by monster hunters. Even more dangerous are the Brood vampires who don't get themselves staked regularly; these clever scourges tend to do things like research rituals to awaken every torpid vampire in the region at once.
VII: Nobody is sure if VII has elders. If they do, they would probobly have used them to wipe out the neonates and ancillae of target cities. On the other hand, the nomad messenger from Bakersfield hasn't shown up in a couple of months... And there have never been proper lines of communication with the prince of Philidelphia... Send a pack of neonates to investigate!
(one of the classic elder vampire solutions to any problem is: "send a pack of neonates at it" and see if that solves the problem. Another elder vampire solution is to wait a year, and see if that clears things up. Particularly old vampires will sometimes wait a decade.)