What could be interesting is if we went with the motif of the Dark Times era of Star Wars, where the Empire is still new, and its evils haven't been revealed. It's everyone for themselves, and if you form a rebellion you'll more than likely be branded as a terrorist.
So... perhaps this Empire hides its evils well. Or, just maybe, they aren't evil. They're a morally gray super-empire simply doing empirical things. The individual is not valued, only the Empire. Rebellions are many, but unorganized, and really, the majority of the populous aren't subjugated...
Basically a world where people are corrupt, and there is little one can really do. The characters have there personal demons, and are all to susceptible to... well everything.
That being said, there are bastions of life in the universe, but they are feeble when compared to the darkness.