I'm looking to flip the script on a game I'm running now, and play a female character or two who experience the end of civilization as we know it, in gritty, nasty detail. I'm picturing she faces everything from biker gangs to escaped criminals...but with a background plot that also involves some mystery and problem-solving (i.e., she has to discover the full extent of what's going on). I'd like the antagonists she meets to have personalities and goals, and not be ONLY interested in sex.
The force that ends the world is up to you, but I'd like an element of mystery and no bizarro anime-style stuff, like everyone being overtaken by irresistable horniness or killer robots. If you go the alien invasion route, make the aliens humanoid and interested in Earth women!