I know a little FATE from Atomic Robo, but never played it, some Pathfinder.
That said, I LOVE canon-based games. LBG jumps out at me... Playing Miko, Yaku or Fubuki would be fun, especially as they start to get into the perversion in their lives, fucking demons for fun instead of picking up guys.
Final Fantasy 7 or X/X-2 are fun, or Marvel. Picture hentai magic or demons creeping into one of those worlds and the heroines needing to adapt to using it themselves to fight back!