The issue that I have with Agent 47 is that the movie is not even out yet. So you would be basing your character sheet on the game rather than on movie content which can differ from one another and in that case the movie would be the way to go for that game. You would have to wait until the movie is out to make sure that the sheet is accurate. If you go with Olyphant's version (the 2007 version) then it's fine.
Regarding characters that have different version/actor, I could accept both if they are in alternate timelines like full reboots. I've agreed to have the BBC Sherlock and the RDJ movie Sherlock in the previous incarnation of the game. I would have loved to watch these two in the same room, trying to outsmart one another (and in BBC's case, finally finding someone who is his match in intellect) I'd agree to have more than one Batman, too.
I'd love to see some Resident Evil characters, Star Wars, Star Trek, more Avengers/Agents of SHIELD, Lord of The Rings, James Bond, TV show Heroes, the humans from Alien(s) who could fight NPC Xenomorphs, Navi from Avatar though they would have to be able to live with oxygen (I know they aren't human characters, but they aren't cartoons/Anime either), The Matrix, Game of Thrones, Buffy/Angel, Spartacus, Lost, Mad Max, Hawaii 5-0 (new or old), Blue bloods, House, Grey's Anatomy, etc. There are a lot of possibilities here.