Hmm. I might just postpone this a bit. I wanted to run a 5e game, but I think Refuge is not the best setting for it... instead, you ought to look at this.
It's much more light-hearted, I think.
If it's an issue of mechanics not matching your needs, i'd highly recommend taking a look at 13th Age: http://www.13thagesrd.com/
It's especially good for games where magical healing is rare or nonexistent, since PC's have a good amount of built-in toughness and self-healing by default.