Personally I don't like messing with Canon, because if it wasn't for the cannon, in most cases, the movie would not be made in the first place. Going around and making huge changes is a slap in the face of fans who have invested time and money into said canon, making it what it is. Taking a character like Bond and making him black for no other reason then to have a black bond is, well, just plain sad. If they did say, a mind transfer into a black guy, or some crazy cosmetic surgery, for undercover work (cause seriously, how can every super-villain out there not have a picture of the guy's face, as bond is less then subtle) at least that could be acceptable.
That being said, sometimes you have to take creative licensing. What makes a good book or a good comic is not the same as making a good movie. It is a different medium, and has to be adjusted accordingly.
I am a fan of the idea of their being different 007's (as explained earlier), but as I don't think it is canon that might be a hard sell. I do like the idea of having other 00 agents explored though. Could make a good series, like 24.