I ran a game awhile back on RPoL.net with huge success.
The game started out as being Inuyasha - OTS (Off the set) Which focused on the lives of the stars behind the anime characters. It was a great game, and we had so much interest it eventually expanded to include writers, directors, producers, crew and various other anime's including Bebop, Trigun, Kingdom Hearts and various others. It was renamed "Off the Set" and ran for a long time until I went off to college and no longer had the time to pay it the attention it needed.
As I find myself with more time and with a wide variety of players on the website (all of which are skilled) I would love to bring the idea back if people are interested.
Players could be from any anime, and it would focus on their life away from the set of their show. Characters would have real life names, and their occupation would be the actor of the show they are best known for.
Any other questions, feel free to ask.