When they should still be pandering to cis het white men, apparently.
Its more about whether or not gender flipping a certain character makes sense. This is all subjective, but personally whilst I found a female Thor very cool in the way they explained it by tweaking already existing mythology to make Thor a rank and not a specific character, Wolverine doesn't have this option. He doesn't come from the highly ritualized society of Asguard, he's a mutant, produced by chance augmented by science. (Its a comic book, so I'll let it slide that a clone of Wolverine would retain the original one's gender.)
Ultimately my preferences aren't of a huge concern, and certainly not a deal breaker. But if they want to diversify their caste of white males, to me it would make more sense to focus on the heroes who are a rank or possess a potent ideology to pass on to their next incarnation. To me, Wolverine is neither of those.
Sexual orientation is obviously different, because no hero is confirmed straight, they are just assume to be so because straight is the assumed norm. Revealing Iceman to be guy showed that it was very easy to diversify the roster in this aspect, you didn't even need to make a new character.