Are you talking about a place to plan to get a new citizenship, or just to live and work? I wasn't really sure.
It really depends what you're looking to do there, and what sort of resources and qualifications you have to begin with. There are lots of interesting places for various tastes, but an American at the bottom in many of them, is only somewhat better than one at the bottom in the US. It can be a very substantial "somewhat" if you're actually on the verge of losing everything, as you can probably get a roof over your head and at least some savings teaching. Still, you want to know how your industry works there and where you fit into it. That is, if you have time and contacts to find out.
It also depends what you want for a social life (or not). Some of us are happy being hermits, some want a busy social life, and some really want a vibrant expat community of their own social class in town. Those are very different sets of needs. There are quite a few developing countries where you could live if you don't need some of them -- and some where you just couldn't. Or... I make very little money and this town bores me, but I pass the time mostly geeking out in some fashion. I don't drink or knock myself out with weekend sports (though I could do those here), and I don't care so much if I blow a lot of time reading news or playing old strategy games (or the occasional good fit roleplay). I don't eat myself too much about having limited face to face contact outside of my job. There is also the question: Are you going to the first place for it to be "the" place, or is it a stepping stone on the way to something better? And there are a lot of other interests you might or might not want or need to have around.
So you might start with a more particular list of what is really important to you in a living situation. Not every country will easily place you near all of them. If you need to be in a bustling major city where you can buy English magazines and get Western fast food, or if you must have wired internet... Or green space, or clear skies, or be allowed to drive yourself.... Or have public transit because you won't drive yourself and don't like to walk for miles first... All of those things will narrow it down at the level of whole countries or regions...
But the map is not the territory. It's great if you can skype with some people there or email, etc. -- But some things you will never appreciate until you go and try. And what particular place and people you land in a country will affect your individual experience in huge ways that you might never have foreseen.