Not that the cribs in 3 were worthwhile once you had one finished; they were all more or less interchangeable, unlike the distinctly different ones available in 2. I can't say I missed boats in 4 since I never spent any time in the water unless necessary anyway, and the clothing options seemed more or less on par (including a lot of things that were DLC in 3, which probably upset some people who bought them), but I can say I never bothered driving around in 4 not just because the super powers made it superfluous, but because they took the Vortex - the best car by far - out of the game, which pretty much erased any interest I had in driving around.
I mean...fuck, guys, why do you keep cutting all the good stuff out of your games? :|
On a much, much more trivial note, I'd forgotten that I missed the completely pointless and unrewarding prostitution minigame from 2. The Boss too good to go hoing these days? For shame, forgetting your roots like that!