I don't have a problem with that world in the early stages of the political and social shifts at all, its just that it gets a bit too extreme for me after a certain point (around 2020 when women cease being considered by men to be humans, there's a limit to how much mysoginy I can stand). I feel though that we could set the game in that universe and still have our lovely game show as long as it wasn't set so late on and women were a little more than walking pieces of meat for men to rape as they pleased.
I don't have any problem with all the extreme things John plans and all the mass rape, torture, bestiality, whipping, bondage, humiliation, watersports, even snuff... I just don't think the xtreme politics of that world need to enter into this game in order for it to work.
Or if you really want to, you can set the 'externals' of the world in that universe but it doesn't impinge on the game show and the RP.
There. I've said my piece, its up to our GM now.