My idea is for a DnD 3.5 E6 rules game set at the onset of the Spellplague era the Thay Red Wizards lose much of their power as do the clergy as magic is in flux and the slaves led by focused leaders and with outside help begin a war of liberation against their masters.
I figure it would be fun kind of like Spartacus: Blood & Sand but with well a fantasy setting and with magic unreliable if there at all. Be good for the classic fighters, rogues and others plus clerics plus there might be room for the odd Expert focusing on technology. Wizards and those who use arcane magic likely won't have access to it.
I figure blood, sex and the whole shebang in the game as the slaves have a large segment rebel. Would be kind of fun and come on the Thayans have it coming. As far as I can tell only Szazz Tam was able to maintain some power and that was due to him being a lich with access to very potent magical artifacts and he has issues.
If anyone cares to run it or play it but I think this could be fun.