Never did like Forgotten Realms..... Between the uber-NPCs and how everything was described, it just wasn't my cup of tea. Plus, I had a falling out with some folks over at the WotC forum play-by-post area and swore off FR for good after that.
Much prefer Eberron, if only because I'm such a psionics fanboy.
*Ahem* But, back on topic. I'm going to save any thoughts about 5e for when it actually comes out. I didn't buy any 4e stuff, but have played it several times and didn't like it too much. Felt too much like a video game turned into a table top game.
I've played at least one game of pretty much every edition, have played the latest version of Castles and Crusades (even played with some of the writers a few years ago at a con), play and run some pathfinder, and started gaming with 3.5e DnD.